C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/57 (2006.01) A61P 15/00 (2006.01) C07C 235/40 (2006.01)
Patent
CA 2385809
The invention provides compounds of formula (I) wherein R1 is optionally substituted C1-6alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, C1-6alkoxy, -NR2R3 or -NR4SO2R5; n is 2 to 6; X is oxygen, sulfur or -CH2-; Y is C1-6alkyl which may be branched- or straight-chain, and may be independently substituted by one or more halo, C1-4alkoxy, hydroxy or C3-7cycloalkyl; wherein the linkage -(CH2)n- and the linkage when X is -CH2-, may be substituted by C1-4alkyl, C1-4haloalkyl, hydroxy, C1-4alkoxy, C1-4haloalkoxy, hydroxyC1-4alkyl, C1-4alkoxyC1-4alkyl, C1-4haloalkoxyC1-4alkyl, C3-7cycloalkyl or C3-7cycloalkylC1-4alkyl. The compounds of the invention are useful in the treatment of inter alia sexual dysfunction, particularly female sexual dysfunction. (see formula one)
Cook Andrew Simon
Stobie Alan
Pfizer Inc.
Smart & Biggar
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