Alkylamine as an antimicrobial agent in ophthalmic compositions

A - Human Necessities – 61 – L

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A61L 12/14 (2006.01) A01N 33/04 (2006.01) A01N 33/12 (2006.01) A01N 41/08 (2006.01) A01N 47/44 (2006.01) A01N 59/00 (2006.01)

Patent

CA 2562267

A multi-purpose contact lens care solution having high activity against fungi and certain bacteria comprising, in liquid aqueous medium, an alkylamine having the following Formula (I) , R1 R2 I R3 where R1 is a C13-17 alkylamine, and R2 and R3 are each independently H or -CH3, and a non-ionic surfactant. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and/or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear.

Solution polyvalente d'hygiène pour lentilles de contact extrêmement efficace contre les champignons et certaines bactéries et contenant, dans un véhicule liquide aqueux, une alkylamine représentée par la formule (I) dans laquelle R1 représente une alkylamine C¿13-17? et R2 et R3 représentent chacun indépendamment H ou -CH¿3? et un tensioactif non ionique. Cette solution peut contenir également des constituants supplémentaires antimicrobiens, un constituant tampon, un constituant induisant la viscosité, un tensioactif, taurine, propylène glycol et/ou un constituant de tonicité. Cette solution permet également d'empêcher des pertes d'intégrité de la membrane tissulaire de l'oeil pendant le port des lentilles de contact.

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