A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4375 (2006.01) A61P 29/00 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2551869
Compounds of the formula (I) which are modulators of chemokine receptor activity useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis, and pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which chemokine receptors are involved.
Des composés de formule (I) qui sont des modulateurs de l'activité des récepteurs de la chimiokine que l'on utilise dans la prévention ou le traitement de certains troubles inflammatoires et immunorégulateurs, de maladies allergiques, de pathologies atopiques, y compris la rhinite allergique, la dermatite, la conjonctivite et l'asthme, ainsi que de pathologies auto-immunes, notamment la polyarthrite rhumatoïde et l'athérosclérose, ainsi que des compositions pharmaceutiques comprenant ces composés et l'utilisation de ces composés et compositions en vue de la prévention ou du traitement de telles maladies dans lesquelles les récepteurs de la chimiokine sont impliqués.
Butora Gabor
Goble Stephen D.
Guiadeen Deodialsingh
Kothandaraman Shankaran
Mills Sander G.
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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