C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2388140
Alkylamino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives of formula (I) are provided wherein R1-R3 are as defined in the application which are useful as inhibitors of p38, along with a process for their manufacture and pharmaceutical preparations containing them.
L'invention concerne des dérivés de dihydropyrimido [4,5-d]pyrimidinone substitués par alkylamino selon la formule (I). Dans cette formule, R<1>-R<3>sont tels que définis dans l'application et sont utiles comme inhibiteurs de p38. L'invention traite également de la fabrication de ces derniers et de préparations pharmaceutiques les contenant.
Dunn James Patrick
Goldstein David Michael
Harris William
Smith Ian Edward David
Welch Teresa Rosanne
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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