Alkylated inositolglycans and their use

Details Alkylated inositolglycans and their use Alkylated inositolglycans and their use

C - Chemistry, Metallurgy

07

H

C07H 15/207 (2006.01) A61K 31/7034 (2006.01) A61P 5/50 (2006.01) C07H 5/06 (2006.01) C07H 11/04 (2006.01)

Patent

CA 2433856

Compounds having a mimetic or antagonistic property of an inositol phosphoglycan, and the uses of these compounds are disclosed, together with the use, e.g. to treat a condition ameliorated by administration of an IPG second messenger or an IPG antagonist thereof. Preferred compounds of the invention are based on the substituted cyclitols, such as the chiro-inositol derivative pinitol (3-O-methyl-chiro-inositol).

L'invention concerne des composés possédant une propriété mimétique ou antagoniste d'un phosphoglycane d'inositol, et les utilisations de ces composés, par exemple pour traiter un état amélioré par l'administration d'un second messager IPG ou d'un antagoniste IPG de celui-ci. Les composés préférés de l'invention sont basés sur des cyclitols substitués, par exemple le dérivé de chiro-inositol pinitol (3-O-méthyl-chiro-inositol).

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