Alkylene diamines

Details Alkylene diamines Alkylene diamines

C - Chemistry, Metallurgy

07

D

167/179, 260/283

C07D 209/48 (2006.01) A61K 31/40 (2006.01) C07C 233/40 (2006.01) C07C 235/34 (2006.01) C07C 237/20 (2006.01) C07C 237/22 (2006.01) C07C 255/57 (2006.01) C07C 317/44 (2006.01) C07D 401/06 (2006.01)

Patent

CA 1340205

A cholinesterase inhibiting agent which contains an alkylene diamine of the formula Image wherein R1 and R2 each independently is a hydrogen atom or a hydrocarbon residue which may optionally be substituted, or R1 and R2 combinedly form, together with the adjacent nitrogen atom, a condensed heterocyclic group, R3 is a hydrogen atom or a hydrocarbon residue or an acyl group which may optionally be substituted and R4 is a hydrogen atom, or R3 and R4 combinedly form a group of the formula Image , Image or -(CH2)m+1- (m being 0, 1 or 2), A is -(CH2)~- (~ being 0, 1 or 2) or -CH=CH-, X is a substituent or substituents and n is an integer of 4 to 7, or a salt thereof, which are useful as cerebral function improving agents for the prevention or treatment of senile dementia, Alzheimer's disease, Huntington's chorea, hyperkinesia, mania and so forth.

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