Alkylenedioxy piperazine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 405/00 (2006.01) C07D 241/04 (2006.01) C07D 409/00 (2006.01)

Patent

CA 1100969

ABSTRACT OF THE DISCLOSURE Alkylenedioxy piperazine compounds of the formula Image and pharmaceutically acceptable acid additions salts thereof are disclosed wherein R1 is diphenylmethyl, or diphenylmethyl wherein a hydrogen atom in the phenyl groups thereof may be replaced by halogen; R2 is hydrogen or alkyl having 1 - 5 carbon atoms and R3 is methylene or ethylene. These compounds are useful for the treatment of vascular and cardiac diseases. Methods for making the compounds and pharmacuetical compositions containing the compounds are also disclosed.

271126

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