Alkylenedioxybenzene derivatives and acid addition salts...

Details Alkylenedioxybenzene derivatives and acid addition salts... Alkylenedioxybenzene derivatives and acid addition salts...

C - Chemistry, Metallurgy

07

D

260/266.3, 260/2

C07D 405/02 (2006.01) C07D 317/58 (2006.01) C07D 317/66 (2006.01) C07D 319/18 (2006.01) C07D 321/10 (2006.01) C07D 405/14 (2006.01)

Patent

CA 1185240

ABSTRACT OF THE DISCLOSURE Alkylenedioxybenzene derivatives are pre- pared and found to be useful as pharmaceutical agents, particularly as hypotensives. These alkylenedioxy- benzene derivatives have the formula (I): Image (I) wherein n is an integer of 1 to 6; Z is -(CH2)m- where m is an integer of 1 to 3 or Image where R1 is hydrogen or C1-C3 alkyl and R2 is C1-C3 alkyl; Y is -CH(OH)-, -?- or Image where R3 is hydrogen, C1-C3 alkyl or C1-C3 acyl; and R is phenyl which may optionally have at least one substituent selected from the group con- sisting of halogen, C1-C5 alkyl, C1-C5 alkoxy and tri- fluoromethyl, or pyridyl; or an acid addition salt thereof.

398437

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