Alkylsulphonamide quinolines

Details Alkylsulphonamide quinolines Alkylsulphonamide quinolines

C - Chemistry, Metallurgy

07

D

C07D 215/52 (2006.01) A61K 31/47 (2006.01) A61P 3/04 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2633129

Compounds of Formula (1), pharmaceutically-acceptable salts, methods of making them, pharmaceutical compositions containing them and methods for their use. The compounds are neurokinin- 3 (NK-3) receptor antagonists and are used in the treatment of diseases such as depression, anxiety, schizophrenia, cognitive disorders, psychoses, obesity, inflammatory diseases, irritable bowel syndrome, inflammatory bowel disorder, emesis, preeclampsia, chronic obstructive pulmonary disease, disorders associated with excessive gonadotrophins and/or androgens including dysmenorrhea, benign prostatic hyperplasia, prostatic cancer and testicular cancer.

Composés de formule (1), leurs sels pharmaceutiquement acceptables, procédés de préparation de ces composés, compositions pharmaceutiques les contenant et procédés pour leur utilisation. Les composés sont des antagonistes du récepteur de la neurokinine 3 (NK-3) et ils sont utilisés dans le traitement de maladies telles que la dépression, l'anxiété, la schizophrénie, les troubles cognitifs, les psychoses, l'obésité, les maladies inflammatoires, le syndrome de l'intestin irritable, le trouble intestinal inflammatoire, les vomissements, la pré-éclampsie, la maladie pulmonaire obstructive chronique, les troubles associés à un excès de gonadotrophines et/ou d'androgènes tels que la dysménorrhée, l'hyperplasie prostatique bénigne, le cancer de la prostate et le cancer des testicules.

Affiliated with

Also associated with

Rating

Alkylsulphonamide quinolines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Alkylsulphonamide quinolines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alkylsulphonamide quinolines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1766804