Alkylthiophenoxypropanolamines

Details Alkylthiophenoxypropanolamines Alkylthiophenoxypropanolamines

C - Chemistry, Metallurgy

07

D

260/604.2

C07D 303/22 (2006.01) C07C 29/36 (2006.01)

Patent

CA 1116636

ALKYLTHIOPHENOXYPROPANOLAMINES Abstract of the Disclosure A new class of alkylthiophenoxypropanolamine derivatives and methods for preparation are described. The compounds have vasodilating and antispasmodic activity, inhibit blood platelet aggregation and are substantially free of beta-adrenergic blocking effects. They are particularly valuable in the treatment of disease states responsive to vasodilation such as obstructive peripheral vascular diseases and cerebral vascular deficiencies. A represent- ative and preferred embodiment of the invention consists of 1-[4- (l-methylethylthio)phenoxy]-3-(octylamino)-2-propanol.

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