Alkynyl alcohols as kinase inhibitors

Details Alkynyl alcohols as kinase inhibitors Alkynyl alcohols as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/82 (2006.01) A61K 31/404 (2006.01) A61K 31/506 (2006.01) C07D 233/88 (2006.01) C07D 407/08 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 471/10 (2006.01) C07D 487/04 (2006.01) C07D 487/06 (2006.01) C07D 487/10 (2006.01) C07D 487/16 (2006.01) C07D 491/10 (2006.01) C07D 495/10 (2006.01)

Patent

CA 2728767

Selected compounds are effective for prophylaxis and treatment of inflammation and inflammatory disorders, such as NIK-mediated disorders. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, inflammation and the like.

Cette invention concerne une sélection de composés efficaces en prophylaxie et en traitement de linflammation et des affections inflammatoires, telles que les affections à NIK. Linvention comprend de nouveaux composés, des analogues, des promédicaments et leurs sels pharmaceutiquement acceptables, des compositions pharmaceutiques et des procédés pour la prophylaxie et le traitement des maladies et dautres pathologies ou affections impliquant, notamment, linflammation.

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