Alkynyl phenyl heteroaromatic glucokinase activators

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 277/46 (2006.01) A61K 31/33 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) C07D 233/88 (2006.01) C07D 401/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2407416

Para-alkynyl phenyl heteroaromatic amides which are active as glucokinase activators to increase insulin secretion which makes them useful for treating type II diabetes.

L'invention concerne des composés hétéroaromatiques à base de para-alkynyle-phényle, qui agissent comme activateurs de la glucokinase pour augmenter la sécrétion d'insuline, d'où leur utilité pour le traitement du diabète de type II.

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