Alkynylpurine compounds and production methods thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 473/00 (2006.01) C07D 473/30 (2006.01) C07D 473/34 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2489468

The present invention relates to alkynylpurine compounds represented by the following formula (I-1) and the formula (I-2): wherein each symbol is as defined in the present specification, salts thereof, and production methods thereof. According to the present invention, a method of producing an alkynylpurine compound and a salt thereof useful as an intermediate for medicament production safely, conveniently and economically from the corresponding purine compound and a salt thereof, as well as an alkynylpurine compound and a salt thereof useful as an intermediate for production of medicaments can be provided.

Cette invention se rapporte à des composés d'alkynylpurine représentés par la formule (I-1) and la formule (I-2), dans lesquelles chaque symbole est tel que défini dans les pièces descriptives de la demande, à des sels de ces composés, et à des procédés de production correspondants. Cette invention permet d'obtenir un procédé de production d'un composé d'alkynylpurine et d'un sel de celui-ci utiles comme intermédiaire dans la production de médicaments de façon sûre, pratique et économique à partir du composé de purine correspondant et d'un sel de celui-ci, ainsi qu'un composé d'alkynylpurine et un sel de celui-ci utiles comme intermédiaire dans la production de médicaments.

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