Allele amplification bias

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2743104

Methods are provided for nucleic acid analysis. In an illustrative method, allele amplification bias is used to amplify preferentially a target nucleic acid that is present in a low allele fraction.

Cette invention concerne des procédés d'analyse d'acides nucléiques. Dans un procédé illustratif, un biais d'amplification d'allèle est utilisé pour amplifier de manière préférentielle un acide nucléique cible qui est présent dans une fraction inférieure de l'allèle.

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