Allele-specific sirna-mediated gene silencing

Details Allele-specific sirna-mediated gene silencing Allele-specific sirna-mediated gene silencing

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A01K 67/027 (2006.01) A61K 31/7105 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2494868

The present invention is directed to small interfering RNA molecules (siRNA) targeted against an allele of interest, and methods of using these siRNA molecules.

La présente invention concerne des molécules d'ARN à faible interférence (ARNsi) dirigées contre un allèle à étudier ainsi que des méthodes d'utilisation desdites molécules ARNsi.

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