C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 9/20 (2006.01)
Patent
CA 2303771
The present invention relates to the use of phospholipase C-.gamma.1 gene for the diagnosis, prognosis and development of treatments of bipolar disorder and/or lithium response. There is provided a method for the identification of patient with susceptibility to bipolar disorder and/or lithium response, which comprises the steps of: a) obtaining a nucleic acid sample of the patient; and b) determining allelic variants of phospholipase C-.gamma.1 gene present in the sample, and wherein certain allelic variants are indicative of a risk of pipolar disorder and/or lithium response.
La présente invention porte sur l'utilisation du gène phospholipase C-.gamma.1 associé au diagnostic, au pronostic et au développement de traitements des troubles bipolaires et/ou de la réaction au lithium. L'invention porte également sur un procédé d'identification du patient susceptible d'être affecté par un trouble bipolaire et/ou réagissant au lithium, ce procédé consistant à: a) prélever sur le patient un échantillon d'acide nucléique; et b) déterminer les allèles du gène phospholipase C-.gamma.1 présent dans l'échantillon, certains allèles présentant un risque de trouble bipolaire et/ou de réaction au lithium.
Alda Martin
Grof Paul
Rouleau Guy A.
Turecki Gustavo
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
University Mcgill
University Of Ottawa
LandOfFree
Allelic variants of the phospholipase c-.gamma.1 gene... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Allelic variants of the phospholipase c-.gamma.1 gene..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Allelic variants of the phospholipase c-.gamma.1 gene... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1467780