Allenyl amines

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 307/34 (2006.01) C07D 213/38 (2006.01) C07D 231/12 (2006.01) C07D 233/54 (2006.01) C07D 277/28 (2006.01) C07D 307/52 (2006.01) C07D 333/04 (2006.01) C07D 333/20 (2006.01) C07D 333/52 (2006.01) C07D 333/58 (2006.01)

Patent

CA 1293511

ABSTRACT The present invention relates to compounds which are allenyl amines, more specifically, .beta.-ethenylidene- (substituted)ethanamines, possessing antihypertensive activity. They are prepared by a novel reaction of a protected N,N-bis-(trimethylsilyl)-4-methoxy-2- butynylamine compound with a metallo-organic compound, with subsequent removal of the silyl protecting groups to provide the desired compound.

554562

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