C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/207, 260/295
C07D 307/34 (2006.01) C07D 213/38 (2006.01) C07D 231/12 (2006.01) C07D 233/54 (2006.01) C07D 277/28 (2006.01) C07D 307/52 (2006.01) C07D 333/04 (2006.01) C07D 333/20 (2006.01) C07D 333/52 (2006.01) C07D 333/58 (2006.01)
Patent
CA 1293511
ABSTRACT The present invention relates to compounds which are allenyl amines, more specifically, .beta.-ethenylidene- (substituted)ethanamines, possessing antihypertensive activity. They are prepared by a novel reaction of a protected N,N-bis-(trimethylsilyl)-4-methoxy-2- butynylamine compound with a metallo-organic compound, with subsequent removal of the silyl protecting groups to provide the desired compound.
554562
Bargar Thomas M.
Barney Charlotte L.
Broersma Robert J.
Matthews Donald P.
Mccarthy James R.
Merrell Dow Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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