Allergenic peptides from cryptomeria japonica and their uses

Details Allergenic peptides from cryptomeria japonica and their uses Allergenic peptides from cryptomeria japonica and their uses

C - Chemistry, Metallurgy

07

K

C07K 14/415 (2006.01) A61K 39/35 (2006.01) C07K 7/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2157980

Disclosed are peptides which essentially consist of T-cell epitope(s) of cedar pollen allergens, homologous peptides thereunto, and immunotherapeutic agents containing such peptides as an effective ingredient. These peptides do not substantially react with immunoglobulin E antibody specific to cedar pollen allergens, and significantly more activate T-cells specific to cedar pollen allergens than a negative control when assayed by the 3H-thymidine uptake method. Thus, the agents can effectively treat and/or the prevent cedar pollinosis without fear of causing side effects when administered to mammals including human.

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