Allergenic proteins and peptides from dog dander and uses...

Details Allergenic proteins and peptides from dog dander and uses... Allergenic proteins and peptides from dog dander and uses...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 39/35 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/08 (2006.01) C12Q 1/02 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2152818

Isolated nucleic acids encoding allergens of Canis familiaris, Can f I or Can f II, are disclosed. A cDNA encoding a peptide having a Can f I activity and a predicted molecular weight of about 19,200 daltons is also described. A cDNA encoding a peptide having Can f II activity and a predicted molecular weight of about 18,200 daltons is also disclosed. The nucleic acids can be used as probes to detect the presence of Can f or Can f II nucleic acid in a sample or for the recombinant production of peptides having a Can f I or Can f II activity. Peptides having a Can f I or Can f II activity can be used in can be used in composition suitable for pharmaceutical administration or methods of diagnosing sensitivity to dog dander.

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