Allergens of alder pollen and applications thereof

Details Allergens of alder pollen and applications thereof Allergens of alder pollen and applications thereof

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) A61K 39/36 (2006.01) C07K 7/04 (2006.01) C07K 14/415 (2006.01) C12N 15/70 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2067144

2067144 9202621 PCTABS00010 This invention provides recombinant DNA molecules which code for polypeptides that exhibit the antigenicity of an Aln g I allergen of alder, Alnus sp., of a Cor a I allergen of hazel or of a Bet v I allergen of birch and other plants of the order Fagales, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. In addition, methods are described for using the polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of allergic diseases.

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