Alleviation of the memory deficits and memory components of...

A - Human Necessities – 61 – K

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A61K 38/51 (2006.01) A01K 67/00 (2006.01) A61K 38/52 (2006.01) A61K 38/53 (2006.01) C07K 14/47 (2006.01) C12N 9/99 (2006.01) G01N 33/00 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2449794

Methods have been developed for alleviating memory problems or psychiatric dysfunctions that have a memory formation component. These methods are based on the finding that a truncated form of an a PKC.zeta.zeta protein is intimately involved in memory formation in animals. This finding is also conetral to methods for determining drugs that will have an effect on memory formaiton or the memory formation component of psychiatric dysfunctions.

L'invention concerne des méthodes mises au point pour soulager les problèmes de mémoire ou les dysfonctionnements psychiatriques comprenant un composant de formation de mémoire. Ces méthodes se basent sur la découverte d'une forme tronquée d'une protéine PKC.zeta., intimement impliquée dans la formation de la mémoire chez les animaux. Cette découverte est également primordiale dans des méthodes visant à définir les médicaments susceptibles d'avoir un effet sur la formation de la mémoire ou les composants de formation de la mémoire des dysfonctionnements psychiatriques.

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