Allophanic acid derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 275/54 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/275 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) C07D 211/26 (2006.01) C07D 211/34 (2006.01) C07D 211/46 (2006.01) C07D 213/82 (2006.01) C07D 295/15 (2006.01) C07D 311/06 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2126038

A B S T R A C T ALLOPHANIC ACID DERIVATIVES The invention concerns allophanic acid derivatives of formula I R1-N(R2)CO-N(R3)CO-X1-Q-X2-G I and pharmaceutically acceptable metabolically labile esters or amides thereof, and pharmaceutically acceptable salts thereof, in which R1, R2, R3, X1, Q, X2 and G have the meanings given in the specification. The invention also concerns processes for the preparation of the allophanic acid derivatives of formula I, pharmaceutical compositions containing them and their use as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa.

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