A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/55 (2006.01) A61K 31/335 (2006.01) A61K 31/38 (2006.01) A61K 31/381 (2006.01) A61K 31/382 (2006.01) A61K 31/395 (2006.01) A61K 31/4025 (2006.01) A61K 31/4365 (2006.01) A61K 31/4436 (2006.01) A61K 45/00 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2441563
The present invention relates to compounds of formulas (IA) and (IB): the preparation thereof, pharmaceutical formulations thereof, and their use in medicine as allosteric adenosine receptor modulators for uses including protection against hypoxia and ischemia induced injury and treatment of adenosine-sensitive cardiac arrhythmias.
L'invention concerne des composés de formules (IA) et (IB), leur préparation, des formules pharmaceutiques élaborées à partir de ceux-ci et leur utilisation en médecine, en tant que modulateurs allostériques des récepteurs de l'adénosine dans des applications, telles que, entre autres, la protection contre l'hypoxie et les lésions tissulaires d'origine ischémique ainsi que le traitement d'arythmies cardiaques sensibles à l'adénosine.
King Pharmaceuticals Research And Development Inc.
Smart & Biggar
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