C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/04 (2006.01) C07H 15/18 (2006.01) C07H 19/04 (2006.01) C07H 19/073 (2006.01) C07H 19/16 (2006.01) C07H 19/173 (2006.01) C07H 23/00 (2006.01)
Patent
CA 2198384
.alpha.-D-pentofuranoside derivatives have the general formula (D), in which R stands for a (C1-C4)alkyl that is non-substituted or substituted one or several times by halogen, (C1-C4)alkyl, (C1-C4)alkoxy and/or phenyl, and R1 stands for [(C6-C20)aryl]k-[(C1-C4)alkyl], (C6-C20)aryl or [(C6-C20)aryl]k- [(C1-C12)alkyl](3-k)Si, in which k = 0 to 3, that are non-substituted or substituted one or several times by halogen, (C1-C4)alkyl, (C1-C4)alkoxy and/or (C6-C20)aryl, or preferably a benzyl that is non-substituted or substituted one or several times by the above substituents. Also disclosed are starting and intermediary compounds, up to furanosides (D) having an analogous structure, processes for preparing said furanosides and their precursors, and their use.
Des dérivés d'.alpha.-D-pentofuranosides ont la formule générale (D), dans laquelle R désigne un alkyle (C¿1?-C¿4?) substitué ou non une ou plusieurs fois par halogène, alkyle (C¿1?-C¿4?), alcoxy(C¿1?-C¿4?) et/ou phényle, et R¿1? désigne un [aryle(C¿6?-C¿20?)]¿k?-[alkyle(C¿1?-C¿4?)], aryle (C¿6?-C¿20?) ou [aryle(C¿6?-C¿20?)]¿k?-[alkyle(C¿1?-C¿12?)]¿(3-k)?Si, k étant compris entre 0 et 3, substitué ou non une ou plusieurs fois par halogène, alkyle (C¿1?-C¿4?), alcoxy (C¿1?-C¿4?) et/ou aryle (C¿6?-C¿20?), ou de préférence un benzyle substitué ou non une ou plusieurs fois par les substituants ci-dessus. L'invention concerne aussi bien des composés de départ et des composés intermédiaires que les furanosides (D) ayant une structure analogue, des procédés de préparation de ces furanosides et de leurs précurseurs, et leur utilisation.
Saischek Jorn
Stadelmann Berndt
Gowling Lafleur Henderson Llp
Saischek Jorn
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