C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2426669
The present invention provides a recombinant expression cassette comprising an .alpha. 1-3 galactosyltransferase promoter operably linked to a polynucleotide for expression. The invention also provides a recombinant mutating cassette comprising a region of homology to an .alpha. 1-3 galactosyltransferase genomic sequence. The cassettes can be employed to express foreign genes or to disrupt the native .alpha. 1-3 galactosyltransferase genomic sequence, particularly within an animal. Thus, the invention also provides transgenic animals and methods for their production and use.
Cette invention a trait à une cassette d'expression de recombinaison comprenant un promoteur de galactosyltransférase-.alpha.-1-3 lié fonctionnellement à un polynucléotide aux fins d'expression. L'invention concerne également une cassette de recombinaison mutante possédant une région d'homologie avec une séquence génomique de galactosyltransférase-.alpha.-1-3. On peut utiliser ces cassettes pour exprimer des gènes étrangers ou pour disloquer la séquence génomique de galactosyltransférase-.alpha.-1-3 endogène, notamment chez l'animal. Cette invention porte ainsi sur des animaux transgéniques ainsi que sur des procédés permettant de les produire et de les utiliser.
Mbm Intellectual Property Law Llp
University Of Pittsburgh Of The Commonwealth System Of Higher Ed
LandOfFree
.alpha.1-3 galactosyltransferase gene and promoter does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with .alpha.1-3 galactosyltransferase gene and promoter, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .alpha.1-3 galactosyltransferase gene and promoter will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1395400