Alpha-2 adrenergic agonists for the treatment of pain

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 233/84 (2006.01) A61K 31/4164 (2006.01) A61K 31/4166 (2006.01) A61P 9/10 (2006.01) A61P 27/06 (2006.01) A61P 29/00 (2006.01) C07D 233/70 (2006.01)

Patent

CA 2603044

A compound is disclosed herein comprising Formula or a pharmaceutically acceptable salt, metabolite, or prodrug thereof; wherein R1, R2, and R3 are independently hydrogen or C1-4 alkyl; A is OH, NH2, or SH; and n is 0, 1, or 2. Methods, compositions, and medicaments related thereto are also disclosed.

La présente invention concerne un composé représenté par la formule (I) ou un sel, un métabolite ou un promédicament pharmaceutiquement acceptable de ce dernier. Dans la formule, R1, R2 et R3 représentent indépendamment hydrogène ou alkyle C1-4; A représente OH, NH2 ou SH; et n représente 0, 1 ou 2. Cette invention porte également sur des méthodes, des compositions et des médicaments correspondants. Formule (I)

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