Alpha-(2-hydroxyphenyl) nitrone compounds, pharmaceutical...

C - Chemistry – Metallurgy – 07 – C

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C07C 291/02 (2006.01) A61K 31/135 (2006.01)

Patent

CA 2337850

Disclosed are novel .alpha.-(2-hydroxyphenyl) nitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for inflammation-related conditions in mammals, such as arthritis, and as analytical reagents for detecting free radicals.

Cette invention a trait à de nouveaux composés de .alpha.-2(2-hydroxyphényl)nitrone et à des compositions pharmaceutiques les renfermant. Ces compositions, qui sont des plus utiles pour traiter des états pathologiques liés à une inflammation chez les mammifères, l'arthrite notamment, font office de réactifs analytiques servant à la détection des radicaux libres.

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