.alpha.-(4-chlorophenyl)-4-[(4-fluorophenyl)-methyl]piperidi...

C - Chemistry – Metallurgy – 07 – D

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C07D 211/18 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2153726

The present invention provides a piperidine derivative of formula (I) Image (I) in which R represents a straight- or branched-chain (C1-C19)alkyl group, a straight- or branched-chain (C2- C19)alkenyl group, a (C3-C6)cycloalkyl group, a cycloalkylmethyl group in which the cycloalkyl moiety has from three to six carbon atoms, a phenyl group which is optionally substituted by a halogen atom or a phenyl methyl group which is optionally substituted by a halogen atom, or an addition salt thereof, in the form of an optically pure enantiomer or of a mixture of enantiomers, a process for making them and their therapeutic application.

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