Alpha 7 nicotinic receptor selective ligands

Details Alpha 7 nicotinic receptor selective ligands Alpha 7 nicotinic receptor selective ligands

C - Chemistry, Metallurgy

07

D

C07D 401/02 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2610795

The invention relates to the design and synthesis of 3-arylidene-anabaseine compounds that exhibit enhanced selectivity toward alpha7 nicotinic receptors. The compounds are expected to be useful in treating a wide variety of conditions, including neurodegenerative conditions such as Alzheimer's Disease, neurodevelopmental diseases such as schizophrenia, and certain peripherally located inflammations mediated by macrophage infiltration.

L~invention se rapporte à la structure et la synthèse de composés 3-arylidène-anabaséine qui présentent une sélectivité renforcée à l~égard des récepteurs nicotiniques alpha 7. On peut s~attendre à ce que ces composés soient utiles lors du traitement de nombreuses variétés de troubles, dont les affections neurodégénératives telles que la maladie d~Alzheimer, les troubles neurodéveloppementaux tels que la schizophrénie, et certaines inflammations périphériques induites par une infiltration par macrophages.

Affiliated with

Also associated with

Rating

Alpha 7 nicotinic receptor selective ligands does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Alpha 7 nicotinic receptor selective ligands, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alpha 7 nicotinic receptor selective ligands will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1950424