.alpha..alpha.-trehalose-6,6'-medium chained lenght...

Details .alpha..alpha.-trehalose-6,6'-medium chained lenght... .alpha..alpha.-trehalose-6,6'-medium chained lenght...

C - Chemistry, Metallurgy

07

H

260/233.1

C07H 13/06 (2006.01)

Patent

CA 1202622

ABSTRACT OF THE DISCLOSURE Disclosed herein is a novel .alpha.,.alpha.-trehalose- 6,6'-medium chain length aliphatic acid diester represented by the following formula (I): Image (I) in which n represents an integer from 6 to 10. This compound is produced, for instance, by converting .alpha.,.alpha.-trehalose into 2,3,2',3'-tetra-o-benzyl- .alpha.,.alpha.-trehalose, and then reacting it with a medium chain length aliphatic acid or an active derivative thereof to form a novel intermediate 2,3,2',3'-tetra-o- benzyl-.alpha.,.alpha.-trehalose-6,6'- medium chain length aliphatic acid diester and further reductively de- benzylating it using a reduction catalyst. The compound according to the invention has an excellent antitumor activity, antibiotic activity and action for delayed- type hypersensitivity, and is useful for pharmaceuticals. Pharmaceutical agents containing an .alpha.,.alpha.-trehalose-6,6'-medium chain length aliphatic acid diester of the formula (I) as an effective ingredient are also disclosed.

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