.alpha.-aminodicarboxylic acid derivatives, their...

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C - Chemistry, Metallurgy

07

C

167/153, 260/480

C07C 235/72 (2006.01) A61K 9/127 (2006.01) A61K 9/42 (2006.01) A61K 47/16 (2006.01) A61K 47/18 (2006.01) C07C 233/47 (2006.01)

Patent

CA 1333719

Disclosed are .alpha.-aminodicarboxylic acid derivatives of the formula: Image where X is C2-C6-alkylene, -CH=CH- or unacetylated or acetylated -CH2-CHOH-, -CHOH-CHOH- or -CH2-CHNH2-, Y and Z are each an aliphatic hydrocarbon radical of 8 to 30 carbon atoms and n is 1 or 2, and their sodium, potassium and ammonium salts. Also disclosed in a process for the preparation of these compounds that are biodegradable, of low toxicity and useful for the preparation of emulsions, microemulsions and gels. Further disclosed is the use of these compounds as carriers for drugs in the pharmaceutical field.

591812

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