.alpha.-chloroketone derivative and process for preparation...

Details .alpha.-chloroketone derivative and process for preparation... .alpha.-chloroketone derivative and process for preparation...

C - Chemistry, Metallurgy

07

C

260/314, 260/557

C07C 323/40 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01)

Patent

CA 1274850

NOVEL .alpha.-CHLOROKETONE DERIVATIVE AND PROCESS FOR PREPARATION THEREOF Abstract of the Disclosure Disclosed is a novel .alpha.-chloroketone derivative as a synthesis intermediate of N-cyano-N'-methyl-N"-(2-((5- methyl-1H-imidazol-4-yl)methylthio)ethyl)guanidine (general name: Cimetidine) which shows all action of controlling the secretion of gastric acid and is valluable as a medicine for remedy of a gastric ulcer. This .alpha.-chloroketone derivative is prepared by reacting d disulfide derivative with sulfuryl chloride and reacting the reaction product with methylvinyl ketone or by reacting a mercapto derivative with 3-chloro-3-buten-2- one. The .alpha.-chloroketone derivative has the formula: Image (I) wherein R stands for a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms or an aryl group.

551222

Affiliated with

Also associated with

Rating

.alpha.-chloroketone derivative and process for preparation... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with .alpha.-chloroketone derivative and process for preparation..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .alpha.-chloroketone derivative and process for preparation... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1313024