Alpha-emitting hydroxyapatite particles

C - Chemistry – Metallurgy – 01 – B

Patent

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Details

C01B 25/32 (2006.01) A61K 51/02 (2006.01) A61P 35/00 (2006.01) C07B 59/00 (2006.01) G21G 4/04 (2006.01) G21G 4/10 (2006.01) A61M 36/06 (2006.01)

Patent

CA 2555435

The present invention provides Hydroxyapatite (HA) incorporating an alpha- emitting radionuclide or an in vivo generator for an alpha-emitting radionuclide. The invention further provides methods for the formation of such HA, pharmaceutical compositions comprising the HA and methods of medical treatment of cancerous or non~cancerous disease including administering the HA or compositions thereof.

La présente invention concerne une hydroxyapatite (HA) incorporant un radionucléide émetteur de rayons alpha ou un générateur <i>in vivo </i> pour un radionucléide émetteur de rayons alpha. L'invention concerne également des procédés destinés à la formation de cette HA, des compositions pharmaceutiques comprenant l'HA et des procédés de traitement médical de maladies cancéreuses ou non cancéreuses, lesdits procédés consistant à administrer l'HA ou ses compositions.

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