Alpha-glucosidase activity inhibitor

A - Human Necessities – 61 – K

Patent

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Details

A61K 36/62 (2006.01) A23L 1/30 (2006.01) A61P 3/10 (2006.01) A61P 43/00 (2006.01) C12N 9/99 (2006.01)

Patent

CA 2544425

[MEANS FOR SOLVING PROBLEMS] Attention has been drawn to Indian lotus among plants, and an Indian lotus extract has been obtained. Effect of the addition of Indian lotus extract on enzymic reaction has been estimated by carrying out reaction with .alpha.-glucosidase and sucrose as its substrate. As a result, it has become apparent that the Indian lotus extract has an .alpha.- glucosidase inhibiting activity. Further, the Indian lotus extract and sucrose have been administered to mice, and the blood sugar level thereof has been measured. As a result, it has become apparent that the blood sugar level is restricted by the Indian lotus extract. Therefore, it has become apparent that the Indian lotus extract has an .alpha.-glucosidase inhibiting activity, and it has been found that the Indian lotus extract can be used in controlling of the blood sugar level.

L'invention concerne une plante appelée lotus indien, et un extrait obtenu dudit lotus indien. L'effet produit par l'adjonction de l'extrait de lotus indien sur une réaction enzymatique a été mesuré par une réaction avec l'alpha-glucosidase utilisant la sucrose comme substrat. Le résultat montre à l'évidence que l'extrait de lotus indien présente une activité inhibitrice de l'alpha-glucosidase. De surcroît, l'extrait de lotus indien et la sucrose ont été administrés à une souris, dont la glycémie a ensuite été mesurée. Le résultat de cette mesure montre de manière évidente: que l'extrait de lotus indien limite la glycémie, qu'il présente une activité inhibitrice de l'alpha-glucosidase, et qu'il peut être utilisé pour réguler la glycémie.

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