.alpha.-glycosyl naringin, and its preparation and uses

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 19/18 (2006.01) A23L 1/09 (2006.01) A23L 1/302 (2006.01) A23L 3/3562 (2006.01) A61K 31/70 (2006.01) C07H 15/26 (2006.01) C07H 17/07 (2006.01) C12N 9/24 (2006.01) C12P 19/14 (2006.01) C12P 19/60 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2041422

Abstract of the Disclosure .alpha.-Glycosyl naringin, a novel naringin derivative wherein equimolar or more D-glucose residues are bound to naringin via the .alpha.-bond, is formed by a saccharide-transferring enzyme in a liquid containing naringin and .alpha.-glucosyl saccharide. The .alpha.-glycosyl naringin is easily recovered from the reaction mixture with a synthetic macroporous resin. .alpha.-Glycosyl naringin, which retains the bitterness inherent to naringin, is superior in water-solubility, free of toxicity, and readily hydrolyzable in vivo into naringin and D-glucose to exhibit the physiological activity inherent to naringin. Thus, .alpha.-glycosyl naringin is favorably usable in vitamin P-enriching agents, foods, beverages, tobaccos, foods, pet foods, pharmaceuticals for susceptive diseases, cosmetics and plas- tics.

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