Alpha helix mimetics and methods relating thereto

Details Alpha helix mimetics and methods relating thereto Alpha helix mimetics and methods relating thereto

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61K 31/53 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2726673

Alpha-helix mimetic structures and compounds represented by the formula (I) wherein the general formula and the definition of each symbol are as defined in the specification, a compound relating thereto, and methods relating thereto, are disclosed. Applications of these compounds in the treatment of medical conditions, e.g., cancer diseases, fibrotic diseases, and pharmaceutical compositions comprising the mimetics are further disclosed.

La présente invention concerne des structures mimétiques dhélice alpha et des composés de formule (I) dans laquelle chaque symbole est tel que défini dans la description, un composé associé, et des procédés correspondants. Linvention concerne également des utilisations de ces composés dans le traitement de conditions médicales, par exemple, des maladies cancéreuses, des maladies fibrotiques, ainsi que des compositions pharmaceutiques comportant cette mimétique.

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