.alpha.-hydroxy fatty acid derivatives and external...

A - Human Necessities – 61 – K

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A61K 31/22 (2006.01) A61K 47/14 (2006.01) C07C 69/675 (2006.01)

Patent

CA 2333701

A novel oily base, which has excellent stability and a low melting point, dose not irritate the skin and is superior feel in use. And an external composition contains the oily base. The present invention is directed to an alpha-hydroxy fatty acid derivatives represented by the general formula (1): (see fig I) wherein R1 represents a straight-chain or branched alkyl group having 10 to 24 carbon atoms, R2 represents a straight-chain or branched alkyl group having 1 to 31 carbon atoms, and R1 represents a straight-chain or branched alkyl group having 11 to 31 carbon atoms, and an external composition contains at least one of the derivatives.

L'invention concerne une nouvelle base d'huile offrant une excellente stabilité et un point de fusion peu élevé, qui n'irrite pas la peau et qui procure une excellente sensation à l'utilisation. L'invention concerne en outre une composition pour usage externe. La base renferme un ou plusieurs dérivés d'acides gras alpha -hydroxy représentés par la formule générale (1), et la composition contient au moins l'un des dérivés considérés. Dans ladite formule, R1 est alkyle C10-24 linéaire ou ramifié; R2 est alkyle C1-31 linéaire ou ramifié; et R3 est alkyle C11-31 linéaire ou ramifié.

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