Alpha ketoamide compounds as cysteine protease inhibitors

Details Alpha ketoamide compounds as cysteine protease inhibitors Alpha ketoamide compounds as cysteine protease inhibitors

C - Chemistry, Metallurgy

07

C

C07C 233/00 (2006.01) C07C 235/00 (2006.01) C07C 237/00 (2006.01) C07C 239/00 (2006.01)

Patent

CA 2602175

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

L'invention concerne des composés qui sont des inhibiteurs des cystéine protéases, en particulier, des cathepsines B, K, L, F, et S et qui servent à traiter des maladies dont la médiation est assurée par ces protéases. L'invention concerne également des compositions pharmaceutiques comprenant ces composés ainsi que des procédés destinés à leur préparation.

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