Alpha-mercapto-amides

Details Alpha-mercapto-amides Alpha-mercapto-amides

C - Chemistry, Metallurgy

07

C

C07C 323/60 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/415 (2006.01) A61K 31/423 (2006.01) A61K 31/428 (2006.01) A61K 31/433 (2006.01) A61K 31/53 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07D 231/40 (2006.01) C07D 241/20 (2006.01) C07D 263/56 (2006.01) C07D 277/64 (2006.01) C07D 285/135 (2006.01)

Patent

CA 2723550

Substituted amides of the general formula (I): with the residues A, R1 and R2 as explained in detail in the description are described. The compounds are suitable in particular as neutral endopeptidase inhibitors and are highly potent.

L'invention porte sur des amides substitués représentés par la formule générale (I), dans laquelle les résidus A, R1 et R2 sont tels qu'expliqués en détail dans la description. Les composés sont très puissants et sont appropriés en particulier comme inhibiteurs de l'endopeptidase neutre.

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