Alpha-methylene gamma lactones as selective cyclooxygenase-2...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/58 (2006.01) A61K 31/34 (2006.01) C07C 317/14 (2006.01) C07C 317/24 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2285567

The invention encompasses the novel compound of Formula (I) as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula (I).

L'invention concerne un nouveau composé de formule (I) et un procédé de traitement des maladies induites par COX-2 consistant à administrer à un patient une quantité non toxique thérapeutiquement efficace d'un composé de formule (I). L'invention concerne aussi certaines compositions pharmaceutiques destinées au traitement de maladies induites par COX-2 comprenant des composés de formule (I).

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