C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 38/34 (2006.01) A61P 37/00 (2006.01) C07K 14/685 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2415938
The invention provides polypeptides containing .alpha.-MSH that can be used to treat diseases characterized by inflammation and/or autoimmunity. Also included in the invention are .alpha.-MSH analogs and nucleic acids encoding polypeptides containing .alpha.-MSH and .alpha.-MSH analogs optionally linked to heterologous sequences. Also included in the invention are methods of delivering .alpha.-MSH containing peptides, .alpha.-MSH analogs, an DNA encoding .alpha.-MSH and .alpha.-MSH analogs.
Cette invention a trait à des polypeptides contenant .alpha.-MSH pouvant être utilisés pour traiter des états pathologiques caractérisés par ne inflammation et/ou une auto-immunité. Elle porte également sur des analogues de .alpha.-MSH ainsi que sur des acides nucléiques codant des polypeptides contenant .alpha.-MSH et sur des analogues de .alpha.-MSH éventuellement liés à des séquences hétérologues. Elle concerne, en outre des méthodes d'administration de peptides contenant analogues de .alpha.-MSH, des analogues de analogues de .alpha.-MSH et de l'ADN codant analogues de .alpha.-MSH et des analogues de .alpha.-MSH.
Aziz Nazneen
Chen Hongmin
Etemad-Moghadam Bijan
Hedley Mary Lynne
Urban Robert
Eisai Inc.
Smart & Biggar
Zycos Inc.
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