C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/04 (2006.01) A61K 31/135 (2006.01) A61K 31/166 (2006.01) A61K 31/225 (2006.01) A61K 31/275 (2006.01) A61K 31/277 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/4164 (2006.01) A61K 31/445 (2006.01) A61K 31/4453 (2006.01) A61K 31/4458 (2006.01) A61K 31/4462 (2006.01) A61K 31/4465 (2006.01) A61K 31/495 (2006.01) A61K 31/5375 (2006.01) A61K 31/54 (2006.01) C07C 217/18 (2006.01) C07C 217/32 (2006.01) C07C 217/54 (2006.01) C07C 219/06 (2006.01) C07C 235/42 (2006.01) C07C 255/54 (2006.01) C0
Patent
CA 2110251
ABSTRACT OF THE DISCLOSURE Compounds of formula (I): Image (I) [wherein: R1 is aryl; R2 is hydrogen, alkyl, alkoxy, halogen or cyano; R3 is a group of formula -B-NR4R5, where R4 and R5 are independently hydrogen, alkyl or substituted alkyl or R4 and R5, together with the nitrogen to which they are attached, form a heterocycle, and B is alkylene or a group of formula -CH2CH(OR6)CH2-, where R6 is hydrogen, alkanoyl, substituted alkanoyl or arylcarbonyl, or a group of formula -D-R7, where D is a single bond or alkylene and R7 is a heterocycle; and A is alkylene; and pharmaceutically acceptable salts and esters thereof] are useful for the treatment and prevention of circulatory diseases and psychosis.
Asai Fumitoshi
Fujimoto Koichi
Ito Tomiyoshi
Koike Hiroyuki
Tanaka Naoki
Marks & Clerk
Sankyo Company Limited
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