Alpha, omega-dicarboximide derivatives as useful...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 491/08 (2006.01) A61K 31/4035 (2006.01) A61K 31/496 (2006.01) C07D 209/48 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2481888

Novel .alpha.,.omega.-dicarboximide derivatives which selectively inhibit binding to the .alpha.-1A adrenergic receptor, a receptor which has been shown to be important in the treatment of benign prostatic hyperplasia. The compounds of the present invention are potentially useful in the treatment of benign prostatic hyperplasia.

Cette invention concerne des nouveaux dérivés de ?,O-dicarboximide qui inhibent sélectivement la liaison avec le récepteur adrénergique ?-¿1A?, récepteur dont on a démontrée qu'il jouait un rôle important dans le traitement de l'hyperplasie prostatique bénigne. Les composés de l'invention conviennent potentiellement bien pour le traitement de l'hyperplasie prostatique bénigne.

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