.alpha.-plasmin inhibitor analogue and a highly productive...

C - Chemistry – Metallurgy – 12 – N

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195/1.2, 195/1.2

C12N 5/10 (2006.01) C07H 21/04 (2006.01) C12N 1/21 (2006.01) C12N 9/68 (2006.01) C12N 9/99 (2006.01) C12N 15/00 (2006.01) C12N 15/15 (2006.01) C12N 15/70 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2005720

- 1 - Abstract An .alpha.2-plasmin inhibitor analog and a highly productive plasmid for expression of .alpha.2-plasmin inhibitor Replacing Leu13 in the natural .alpha.2-plasmin inhibitor amino acid sequence by Phe13 leads to an effective .alpha.2-plasmin inhibitor analogue. It can be prepared by genetic engineering, especially in an expression system using E. coli host cells.

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