C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/547 (2006.01) A61K 31/675 (2006.01) C07F 9/58 (2006.01) C07F 9/59 (2006.01) C07F 9/6503 (2006.01) C07F 9/6509 (2006.01) C07F 9/6512 (2006.01) C07F 9/6527 (2006.01) C07F 9/6536 (2006.01) C07F 9/6539 (2006.01) C07F 9/6541 (2006.01)
Patent
CA 2420851
The present invention relates to novel .alpha.-substituted-.beta.- aminoethylphosphonate and .alpha.-substituted-.beta.-aminovinylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoproteins) and for lowering plasma levels of total cholesterol.
La présente invention concerne de nouveaux dérivés .szlig.-aminoéthylphosphonates .alpha.-substitués et .szlig.-aminovinylphosphonates .alpha.-substitués et leur utilisation pour réduire dans le plasma les taux des lipoprotéines apo (a), Lp (a), apo B et apo B associées (lipoprotéines de faible densité et lipoprotéines de très faible densité) et pour réduire dans le plasma les taux de cholestérol total. .
Azoulay Raymond
Bentzen Craig Leigh
Diep Vinh Van
Eschenhof Harald
Ife Robert John
Goudreau Gage Dubuc
Ilex Oncology Research S.a.
Ilex Products Inc.
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