Alpha-substituted n-sulfonyl gylcine amides antagonists of...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 311/19 (2006.01) C07C 311/44 (2006.01) C07D 209/08 (2006.01) C07D 211/16 (2006.01) C07D 211/22 (2006.01) C07D 211/62 (2006.01) C07D 211/70 (2006.01) C07D 217/06 (2006.01) C07D 295/185 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2725140

Disclosed is a compound of formula (I). Wherein R1, R2 Ar and Cy are as defined herein, or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions of the compound of formula (I), methods of making the compounds of formula I, and methods of using the compounds of formula (I) to treat a disorder associated with activation of CCR10.

L'invention porte sur un composé de formule (I) dans laquelle R1, R2, Ar et Cy sont tels que définis dans l'invention, o sur un sel acceptable d'un point de vue pharmaceutique de ce composé. L'invention porte aussi sur des compositions pharmaceutiques du composé de formule (I), sur des procédés de préparation des composés de formule I et sur des procédés d'utilisation des composés de formule (I) pour traiter un trouble associé à une activation du CCR10.

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