.alpha.-substituted ureidobenzylpenicillanic acid and...

C - Chemistry – Metallurgy – 07 – D

Patent

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260/114.3

C07D 499/64 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1203530

Abstract of the Disclosure: .alpha.-Substituted ureidobenzylpenicillanic acids of the formula Image (wherein R1, X and Y are as defined in the description) and pharmaceutically acceptable salts thereof a process for pre- paring the same and bactericial composition comprising the above penicillanic acid or the salt and a pharmaceutically acceptable carrier are disclosed. The acids and salts thereof have high antibacterial activities against particularly Gram-positive and Gram-negative bacteria, particularly those of the genus Pseudomonas.

383181

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