C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 227/32 (2006.01) C07C 227/16 (2006.01) C07C 253/30 (2006.01)
Patent
CA 2358560
Methods for stereoselective substitution in which a (mono or un)-.alpha.- substituted unprotected .beta.-amino ester compound or salt thereof is reacted with an aliphatic electrophile in the presence of a base selected from alkyl lithium compounds, lithium hybride, lithium amide, lithium dialkyl amides and alkali hexamethyldisilylamines.
L'invention concerne des procédés de substitution stéréosélective dans lesquels on met à réagir un composé de beta -amino ester non protégé (mono ou non)- alpha substitué, ou un sel de celui-ci, avec un électrophile aliphatique en présence d'une base sélectionnée dans le groupe constitué par des composés de lithium alkylés, un hydrure de lithium, un amide de lithium, des amides dialkylés de lithium et des hexaméthyldisilylamines alcalines.
Chandramouli Sithamalli V.
O'brien Michael K.
Powner Tory H.
Aventis Pharmaceuticals Inc.
Aventis Pharmaceuticals Products Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
LandOfFree
.alpha.-substitution of unprotected .beta.-amino ester... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with .alpha.-substitution of unprotected .beta.-amino ester..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .alpha.-substitution of unprotected .beta.-amino ester... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1896263