.alpha.-sulfonylamino hydroxamic acid inhibitors of matrix...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/197 (2006.01) A61K 31/00 (2006.01) A61K 31/195 (2006.01) A61K 31/216 (2006.01) A61K 31/222 (2006.01) A61K 31/351 (2006.01) A61K 31/395 (2006.01) A61K 31/438 (2006.01) A61K 31/4453 (2006.01) A61K 31/4465 (2006.01) A61K 31/4468 (2006.01) A61K 31/495 (2006.01) A61K 31/5375 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2321593

The present invention relates to a use of a compound of the formula (I): (see formula I) wherein A, X1, X2, and Q are as defined herein, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition thereof, in the treatment of a disease, condition or disorder of the peripheral or central nervous system, including but not limited to Alzheimer's disease, stroke/cerebral ischemia, head trauma, spinal cord injury, multiple sclerosis, amyotrophic lateral sclerosis, Huntington's disease, Parkinson's disease, migraine, cerebral amyloid angiopathy, AIDS, age-related cognitive decline, mild cognitive impairment and prion diseases.

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