Alpha1-acid glycoprotein purification process and product

Details Alpha1-acid glycoprotein purification process and product Alpha1-acid glycoprotein purification process and product

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 35/16 (2006.01) C07K 1/18 (2006.01) C07K 14/435 (2006.01)

Patent

CA 2171832

Purified .alpha.1-acid glycoprotein and a process for preparing purified .alpha.1-acid glycoprotein. The process comprises providing an impure protein fraction, binding contaminants, but not .alpha.1-acid glycoprotein, to a cation-exchange medium, and binding .alpha.1-acid glycoprotein to a anion-exchange medium, and eluting the .alpha.1-acid glycoprotein from the anion-exchange medium.

Cette invention concerne une glycoprotéine 'alpha'1-acide purifiée et un procédé de préparation de cette dernière selon lequel on place une fraction de protéine unique, des contaminants de liaison, mais pas une glycoprotéine 'alpha'1-acide, dans un milieu échangeur de cations, on lie la glycoprotéine 'alpha'1-acide avec un milieu échangeur d'anions, puis on élue la glycoprotéine 'alpha'1-acide du milieu échangeur d'anions.

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